Viruses & Diabetes Update

Jones G, Muriello M, Patel A, Logan L. Enteroviral Meningoencephalitis Complicated by Central Diabetes Insipidus in a Neonate: A Case Report and Review of the Literature. J Pediatric Infect Dis Soc. 2015 Jun;4(2):155-8.

Rasigade JP, Dunyach-Rémy C, Sapin A, Messad N, Trouillet-Assant S, Dupieux C, Lavigne JP, Laurent F. A Prophage in Diabetic Foot Ulcer-Colonizing Staphylococcus aureus Impairs Invasiveness by Limiting Intracellular Growth. J Infect Dis. 2016 Nov 15;214(10):1605-1608.

Hulme KD, Gallo LA, Short KR. Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination? Front Microbiol. 2017 May 22;8:861.

Kfoury KAE, Romond MB, Scuotto A, Alidjinou EK, Dabboussi F, Hamze M, Engelmann I, Sane F, Hober D. Bifidobacteria-derived lipoproteins inhibit infection with coxsackievirus b4 in vitro. Int J Antimicrob Agents. 2017 Jun 5.

Dear Friends,

this week we have several papers of interest:

preclinical evaluation of a CoxB1 vaccine (Finland-Sweden) http://dx.doi.org/10.1016/j.vaccine.2017.05.057;
miRNAs produced in islet cells upon CoxB5 infection may influence the expression of diabetes susceptibility genes (Craig http://www.ncbi.nlm.nih.gov/pubmed/26558682);
the interesting observation of complement components being produced in brain during viral infection (similar studies could be done in viral diabetes);
aggegates of bifidobacteria lipoproteins may have protective effect against CoxB4 (Hober);
confluence of "different" epidemics in the US: HCV, diabetes, obesity, neprhopathy;
diabetes as predisposing factor to severe influenza;
finally, diabetic ulcers infected with Staph aureus successfully treated with phages (J Infect Dis).

Have a nice week end,

Antonio

Antonio Toniolo, MD, FAMH Ordinario di Microbiologia Medica Università dell'Insubria, Dip. Biotecnologie e Scienze della Vita Direttore, Laboratorio di Microbiologia Medica Ospedale di Circolo e Fondazione Macchi Viale Borri 57 21100 Varese, Italy

Tel. +39-0332-278309 Fax +39-0332-260.017

Cell. 338-801.0722 antonio.toniolo@uninsubria.it antonio.toniolo@asst-settelaghi.it

antonio.toniolo@gmail.com