Diabetes & Virus - Update.

Dear Friends,

This week we have two major contributions:

- one for the Hyoty's group shows that detection of enteroviruses in stool precedes by months the appearance of diabetes autoantibodies in children;

- the second one shows that In NOD mice pancreatic islet cells may release microvesicles carrying endogenous retrovirus (antigens Env and Gag). Env is a target of autoantibodies and Gag contributes to T-cell-mediated islet destruction.

Yours, Antonio

Enterovirus detection in stools precedes autoantibodies by months - Diabetologia 2017-01

Endogenous Retroviruses linked to diabetes autoimmunity in ND mice - Eur J Immunol - 2017 -01