Diabetes & Virus - Update.
This week we have two major contributions:
- one for the Hyoty's group shows that detection of enteroviruses in stool precedes by months the appearance of diabetes autoantibodies in children;
- the second one shows that In NOD mice pancreatic islet cells may release microvesicles carrying endogenous retrovirus (antigens Env and Gag). Env is a target of autoantibodies and Gag contributes to T-cell-mediated islet destruction.