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September 18, 2017

Dear Friends,

Possibly you have heard that Gian Franco Bottazzo left us prematurely. Gian Franco has been a great scientist, a leader in diabetes immunology, and a good friend to many of us. You can read his full obituary and a summary of his achievements on the VIDIS g...

September 18, 2017

Gian Franco Bottazzo, 'father of islet cell autoantibodies' dies prematurely at 71.

Gian Franco Bottazzo, Italian physician and researcher, was born in Venice, Italy, in 1946. He obtained his M.D. degree from Padua University in 1971, completed post-graduate studies in...

September 13, 2017

Dear Friends,

This week there are  two interesting papers on the IFIH1 gene and its influence on diabetes and infection. http://www.ncbi.nlm.nih.gov/pubmed/28553952 http://www.ncbi.nlm.nih.gov/pubmed/28716935

In addition, a contribution by Hober and his group showing tha...

July 17, 2017

Mallol C, Casana E, Jimenez V, Casellas A, Haurigot V, Jambrina C, Sacristan V, Morró M, Agudo J, Vilà L, Bosch F. AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice. Mol Metab. 2017;6(7):664-680. doi: 10.1016/j.molmet...

May 8, 2017

Dear Friends,

This week we have two virology papers:

1) Mutation rate in RNA viruses, limits and fitness - concepts relevant to enteroviruses http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006254;

2) Norovirus Abs in sera collected over 4 decades.

...

April 27, 2017

Dear Friends,

this week we have:

1) an interesting case report showing that antiviral therapy for HCV leads to insulin withdrawal in type 2 diabetes (an example for interventional studies);

http://www.ncbi.nlm.nih.gov/pubmed/28413215

2) a study showing that a "vaccine stim...

April 18, 2017

Dear Friends,

This week we have a significant report from Japan: fulminant diabetes strongly associated with cytomegalovirus expression in pancreatic islets (full text not yet available). http://www.ncbi.nlm.nih.gov/pubmed/28398495

An important contribution to reovirus...

March 3, 2017

Dear Friends,

Last week I attended the nPOD meeting in Fort Lauderdale.

Here are two papers of general interest:

One on virus sequencing methods, applications, perspectives (instructive for typing diabetes-associated enteroviruses.

- Houldcroft, Charlotte; Beale, Matt...

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September 18, 2017

September 13, 2017